Research
Cell Injury Controller II
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The Cell Injury Controller II is an electronically controlled pneumatic device that allows the study of morphologic, physiologic and biochemical responses of tissue-cultured cells to trauma.
Depending on the cell type, the degree of injury and the culture conditions, the injured cells may die or repair. Therefore, the system can be employed to study the responses to trauma, including cell injury, repair, death or pharmacologic intervention.
The CIC II has been designed for use with a patented, commercially available tissue culture system from Flexcell International Corp. in Hillsborough, N.C. Tissue cultures are grown in culturing wells with stretchable Silastic® membrane bottoms. The CIC II regulates the flow of compressed gas to rapidly pressurize individual culture wells, causing a radial stretch injury to the culture. Injury severity is determined by controlling the flow of gas in and out of the sealed culture well and the peak pressure is captured to provide an accurate indicator of radial stretch.
The CIC II accepts both the Flex I® 29.45cm2 culturing trays, which were used with the earlier CIC Model 94A, and the BioFlex® 57.75cm2 culturing trays.
For more information on the CIC II, or to place an order, please contact us.